Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 3/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31478961 | 0.84 | CKS1B (0.36) | JAK3ALOX5APFEN1CKS1BSKP1 | |
| SCHEMBL31479568 | 0.84 | CKS1B (0.41) | BTKRETPDE10ASYKCKS1B | |
| SCHEMBL31479559 | 0.84 | IRAK4 (0.40) | DPP4 | |
| SCHEMBL31479874 | 0.79 | TRPV3 (0.40) | JAK3ALOX5APFEN1 | |
| SCHEMBL31480038 | 0.78 | RET (0.36) | RET | |
| SCHEMBL31479719 | 0.77 | JAK3 (0.57) | BTKJAK3EGFRLCKAURKA | |
| SCHEMBL31479288 | 0.76 | ENPP2 (0.36) | BTKJAK3RETALOX5APFEN1 | |
| SCHEMBL31479079 | 0.74 | CKS1B (0.36) | RETCKS1BSKP1SKP2 | |
| SCHEMBL31479868 | 0.73 | PDK4 (0.41) | JAK3PDE10A | |
| SCHEMBL31479357 | 0.72 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |