Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479079 | 0.89 | CKS1B (0.36) | CKS1BSKP1SKP2RETPARP1 | |
| SCHEMBL31479421 | 0.84 | BTK (0.43) | CKS1BSKP1SKP2RETPDE10A | |
| SCHEMBL31479288 | 0.83 | ENPP2 (0.36) | RETNTRK1SYKMEN1KMT2A | |
| SCHEMBL31479882 | 0.80 | KDM1A (0.36) | RETMEN1KMT2AKCNH2PLK1 | |
| SCHEMBL31478961 | 0.80 | CKS1B (0.36) | CKS1BSKP1SKP2KCNA3 | |
| SCHEMBL31480019 | 0.79 | GPR119 (0.40) | — | |
| SCHEMBL31478957 | 0.78 | SUV39H2 (0.37) | CKS1BSKP1SKP2RETPARP1 | |
| SCHEMBL31478962 | 0.77 | CKS1B (0.38) | CKS1BSKP1SKP2RETPARP1 | |
| SCHEMBL31479381 | 0.76 | CDK9 (0.35) | — | |
| SCHEMBL24694567 | 0.74 | MEN1 (0.59) | CKS1BSKP1SKP2PARP1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |