Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479712 | 0.90 | MEN1 (0.44) | MEN1KMT2AKCNH2DRD2KAT8 | |
| SCHEMBL31478983 | 0.84 | MEN1 (0.35) | MEN1KMT2AKCNH2IRAK4ALOX5AP | |
| SCHEMBL31479730 | 0.83 | ALOX5AP (0.36) | MEN1KMT2AKCNH2ALOX5APFEN1 | |
| SCHEMBL31479079 | 0.82 | CKS1B (0.36) | MEN1KMT2AKCNH2PLK1NPY5R | |
| SCHEMBL31479882 | 0.82 | KDM1A (0.36) | MEN1KMT2AKCNH2DRD2KAT8 | |
| SCHEMBL31479288 | 0.81 | ENPP2 (0.36) | MEN1KMT2AKCNH2PLK1ALOX5AP | |
| SCHEMBL31479427 | 0.81 | MEN1 (0.42) | MEN1KMT2AKCNH2DRD2KAT8 | |
| SCHEMBL31479073 | 0.80 | MEN1 (0.34) | MEN1KMT2AKCNH2PLK1IRAK4 | |
| SCHEMBL31479690 | 0.80 | MEN1 (0.34) | MEN1KMT2AKCNH2PLK1IRAK4 | |
| SCHEMBL31479345 | 0.80 | JAK2 (0.34) | MEN1KMT2AKCNH2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |