Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 5/20 | 0.43 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480402 | 0.82 | PARP1 (0.46) | PER2CRY2PARP1ALDH1A1NPC1 | |
| SCHEMBL21314781 | 0.81 | RAPGEF3 (0.39) | PER2CRY2PARP1ALDH1A1NPC1 | |
| SCHEMBL31479049 | 0.78 | ATM (0.43) | PER2CRY2PARP1ALDH1A1NPC1 | |
| SCHEMBL16480393 | 0.74 | TDP1 (0.47) | PER2CRY2TSHRMAPK1HTR7 | |
| SCHEMBL16480422 | 0.73 | ALOX5 (0.46) | PER2CRY2ALDH1A1TSHRMEN1 | |
| SCHEMBL16480407 | 0.73 | PER2 (0.40) | PER2CRY2PARP1SRD5A1SMN1; SMN2 | |
| SCHEMBL20528241 | 0.71 | PARP1 (0.39) | PER2CRY2PARP1P2RX7HTT | |
| SCHEMBL18191684 | 0.71 | PARP1 (0.39) | PER2CRY2PARP1P2RX7HTT | |
| SCHEMBL16480401 | 0.71 | NOTUM (0.54) | PARP1SRD5A1KMT2A | |
| SCHEMBL16480455 | 0.70 | PARP1 (0.41) | PARP1P2RX7ALDH1A1HTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |