Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31479380 | 0.93 | PREP (0.38) | PREPMAPTLMNAGPR119TP53 | |
| SCHEMBL31478971 | 0.92 | PREP (0.37) | PREPMAPTLMNAGPR119RET | |
| SCHEMBL31478999 | 0.92 | PREP (0.40) | PREPMAPTGPR119NTRK1MEN1 | |
| SCHEMBL31479143 | 0.89 | MAPT (0.40) | MAPTLMNAGPR119TP53RET | |
| SCHEMBL31479454 | 0.89 | PREP (0.38) | PREPMAPTLMNAGPR119TP53 | |
| SCHEMBL31479282 | 0.87 | PREP (0.38) | PREPMAPTLMNAGPR119TP53 | |
| SCHEMBL31479050 | 0.86 | PREP (0.41) | PREPMAPTGPR119MEN1KMT2A | |
| SCHEMBL31479921 | 0.84 | PREP (0.39) | PREPMAPTLMNAGPR119TP53 | |
| SCHEMBL31479503 | 0.83 | PREP (0.37) | PREPGPR119NTRK1 | |
| SCHEMBL31478993 | 0.82 | ENPP2 (0.37) | MAPTLMNAGPR119TP53RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |