SCHEMBL31479928

SCHEMBL31479928

CCN(C(=O)c1cc(F)ccc1-c1cc(C2(F)CN(C(=O)OC(C)(C)C)C2)cn2cncc12)C(C)C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
GPR119 Q8TDV5 5/20 0.33
JAK2 O60674 8/20 0.33
JAK1 P23458 8/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KCNH2 Q12809 1/20 0.33
HCRTR1 O43613 2/20 0.33
HCRTR2 O43614 2/20 0.33
CNR2 P34972 1/20 0.31
F2RL1 P55085 1/20 0.31
GPBAR1 Q8TDU6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31479353 0.93 ALOX5AP (0.35) ALOX5APFEN1GPR119JAK2JAK1
SCHEMBL31479531 0.88 PREP (0.37) JAK1MEN1KMT2AKCNH2
SCHEMBL31479452 0.87 ALOX5AP (0.36) ALOX5APFEN1GPR119JAK2JAK1
SCHEMBL31479890 0.84 HCRTR1 (0.36) MEN1KMT2AKCNH2HCRTR1HCRTR2
SCHEMBL31479996 0.84 GPR119 (0.37) GPR119MEN1KMT2A
SCHEMBL31479528 0.83 GPR119 (0.41) GPR119
SCHEMBL31479315 0.82 PDK4 (0.36) ALOX5APFEN1GPR119HCRTR1HCRTR2
SCHEMBL31479477 0.82 GPR119 (0.40) ALOX5APFEN1GPR119GPBAR1
SCHEMBL31479129 0.82 GPR119 (0.40) ALOX5APFEN1GPR119GPBAR1
SCHEMBL31479929 0.82 GPR119 (0.40) ALOX5APFEN1GPR119GPBAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067111-A1 MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION 苏州必扬医药科技有限公司 2025-04-03 WO disclosed