Styrene

Styrene

SCHEMBL3148009

C=Cc1ccccc1.CCCCC(=Cc1ccccc1)CC

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
ALDH1A1 P00352 2/20 0.45
TSHR P16473 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
PTGS2 P35354 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
KDM1A O60341 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NR1I2 O75469 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
ELANE P08246 1/20 0.34
EGFR P00533 1/20 0.33
AKR1C3 P42330 1/20 0.33
HDAC3 O15379 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9311749 0.92 LMNA (0.53) LMNAALDH1A1TSHRTDP1PTGS2
Styrene SCHEMBL3151653 0.90 ALDH1A1 (0.48) LMNAALDH1A1TSHRTDP1CES2
SCHEMBL6859722 0.86 LMNA (0.60) LMNATDP1PTGS2CES2CES1
Styrene SCHEMBL5095941 0.86 ALDH1A1 (0.56) LMNAALDH1A1TSHRTDP1KDM1A
SCHEMBL10899476 0.85 TDP1 (0.61) LMNAALDH1A1TDP1CES2CES1
SCHEMBL9311704 0.85 TDP1 (0.61) LMNAALDH1A1TDP1CES2CES1
SCHEMBL93497 0.84 LMNA (0.56) LMNAALDH1A1TSHRTDP1PTGS2
SCHEMBL3839387 0.82 LMNA (0.47) LMNAALDH1A1TSHRTDP1PTGS2
SCHEMBL8741682 0.81 LMNA (0.62) LMNATDP1PTGS2CES2CES1
SCHEMBL9311873 0.81 LMNA (0.53) LMNAALDH1A1TSHRTDP1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4366515-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2024-05-15 EP claimed
WO-2023280521-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2023-01-12 WO claimed
EP-0771052-B1 Telephone line connector RAYCHEM CORP (US) 1998-10-14 EP claimed
US-5470634-A Cover for air-bag installation AUTOLIV DEVELOPMENT AB (SE) 1995-11-28 US claimed
EP-4366515-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2024-05-15 EP disclosed
CN-116535617-A Poly dicyclopentadiene/caryophyllene copolymer with adjustable mechanical property and preparation method thereof 吉林大学 2023-08-04 CN disclosed
WO-2023280521-A1 HOSE PIPE REHAU Industries SE & Co. KG (DE) 2023-01-12 WO disclosed
WO-2019076815-A1 TONOMETER CONE ARTEMA SRL (IT) 2019-04-25 WO disclosed
EP-1675927-B1 COMPOSITION AND METHOD RELATING TO A HOT MELT ADHESIVE FULLER H B LICENSING FINANC (US) 2010-02-17 EP disclosed
US-20070082973-A1 Composition and method relating to a hot melt adhesive H.B. FULLER LICENSING & FINANCING, INC. 2007-04-12 US disclosed
US-7173076-B2 Composition and method relating to a hot melt adhesive H.B. FULLER LICENSING & FINANCING INC (US) 2007-02-06 US disclosed
EP-1675927-A1 COMPOSITION AND METHOD RELATING TO A HOT MELT ADHESIVE H.B. FULLER LICENSING & FINANCING, INC. (US) 2006-07-05 EP disclosed
WO-2005023951-A1 COMPOSITION AND METHOD RELATING TO A HOT MELT ADHESIVE H.B. FULLER LICENSING & FINANCING, INC. (US) 2005-03-17 WO disclosed
US-20050049342-A1 Composition and method relating to a hot melt adhesive ROYAL ADHESIVES AND SEALANTS, LLC 2005-03-03 US disclosed
US-5470634-A Cover for air-bag installation AUTOLIV DEVELOPMENT AB (SE) 1995-11-28 US disclosed