SCHEMBL31480146

SCHEMBL31480146

COC(=O)c1ccc(C2CC3(CCN2)CC(F)(F)C3)c(N2CC(F)(F)C2)n1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 2/20 0.34
CNR2 P34972 16/20 0.33
DPP4 P27487 1/20 0.32
PDE2A O00408 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31480606 0.91 CRBN (0.33) CRBNDPP4
SCHEMBL31480318 0.90 MAPK1 (0.33) CRBNCNR2
SCHEMBL31480481 0.84 MAPT (0.30) CRBNCNR2
SCHEMBL31480488 0.82 MAPT (0.31) DPP4
SCHEMBL31480395 0.80 NISCH (0.34) CRBN
SCHEMBL31480450 0.79
SCHEMBL31480086 0.79
SCHEMBL31480574 0.79 SCN9A (0.31)
SCHEMBL31140832 0.77 MAPK1 (0.40) DPP4
SCHEMBL31561368 0.77 MAPK1 (0.40) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054361-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2025-03-13 WO disclosed