SCHEMBL31480574

SCHEMBL31480574

COC(=O)c1ccc(C2CC3(CCN2)CC(F)(F)C3)c(NC(C)C(N)=O)n1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.31
FPR2 P25090 1/20 0.31
PIM1 P11309 2/20 0.30
PIM2 Q9P1W9 2/20 0.30
SYK P43405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31480488 0.91 MAPT (0.31)
SCHEMBL31480086 0.85
SCHEMBL31480481 0.84 MAPT (0.30)
SCHEMBL31480450 0.82
SCHEMBL31480146 0.79 CRBN (0.34)
SCHEMBL31480606 0.78 CRBN (0.33)
SCHEMBL31480509 0.77 CRBN (0.32)
SCHEMBL31480332 0.77 CRBN (0.32)
SCHEMBL31480318 0.76 MAPK1 (0.33)
SCHEMBL31561368 0.74 MAPK1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054361-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2025-03-13 WO disclosed