SCHEMBL31480488

SCHEMBL31480488

COC(=O)c1ccc(C2CC3(CCN2)CC(F)(F)C3)c(NC(C)C)n1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31480574 0.91 SCN9A (0.31)
SCHEMBL31480086 0.85
SCHEMBL31480450 0.85
SCHEMBL31480481 0.85 MAPT (0.30) MAPT
SCHEMBL31480606 0.83 CRBN (0.33) DPP4
SCHEMBL31480146 0.82 CRBN (0.34) DPP4
SCHEMBL31480332 0.80 CRBN (0.32) MAPT
SCHEMBL31480509 0.80 CRBN (0.32) MAPT
SCHEMBL31480318 0.79 MAPK1 (0.33)
SCHEMBL31140832 0.77 MAPK1 (0.40) MAPTDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025054361-A1 COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2025-03-13 WO disclosed