Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480330 | 0.88 | PTGER4 (0.37) | KDM4EHSD17B10SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31480383 | 0.86 | KCNH2 (0.31) | KDM4EALDH1A1MAPTNPSR1KCNH2 | |
| SCHEMBL31480175 | 0.85 | PTGER4 (0.39) | KDM4EHSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL31480092 | 0.82 | PTGER4 (0.32) | KDM4EALDH1A1MAPTNPSR1KCNH2 | |
| SCHEMBL31480467 | 0.82 | ALDH1A1 (0.35) | KDM4EALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL31480447 | 0.82 | MAPT (0.33) | KDM4EHSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL31480499 | 0.81 | CNR2 (0.36) | KDM4EALDH1A1LRRK2 | |
| SCHEMBL31480395 | 0.76 | NISCH (0.34) | KDM4EHSD17B10SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31480080 | 0.76 | KMT2A (0.36) | KDM4EHSD17B10SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25318693 | 0.74 | NPC1 (0.40) | KDM4EHSD17B10SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |