Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MDH1 | P40925 | 1/20 | 0.31 |
| ▸ | MDH2 | P40926 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31480467 | 0.94 | ALDH1A1 (0.35) | MAPTNPSR1ALDH1A1KDM4EMAPKAPK2 | |
| SCHEMBL31480175 | 0.84 | PTGER4 (0.39) | MAPTNPSR1ALDH1A1KDM4EMAPKAPK2 | |
| SCHEMBL31480330 | 0.84 | PTGER4 (0.37) | MAPTNPSR1ALDH1A1KDM4EMAPKAPK2 | |
| SCHEMBL31480383 | 0.82 | KCNH2 (0.31) | MAPTNPSR1ALDH1A1KDM4E | |
| SCHEMBL31480228 | 0.82 | KDM4E (0.35) | MAPTNPSR1ALDH1A1KDM4EHPGD | |
| SCHEMBL31480092 | 0.82 | PTGER4 (0.32) | MAPTNPSR1ALDH1A1KDM4EMDH1 | |
| SCHEMBL31480395 | 0.80 | NISCH (0.34) | MAPTNPSR1ALDH1A1KDM4EMAPKAPK2 | |
| SCHEMBL31480436 | 0.80 | VCAM1 (0.42) | MAPTNPSR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL31480262 | 0.79 | ALDH1A1 (0.38) | MAPTNPSR1ALDH1A1KDM4EMAPKAPK2 | |
| SCHEMBL25318693 | 0.79 | NPC1 (0.40) | MAPTALDH1A1KDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |