Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.61 |
| ▸ | HTR7 | P34969 | 4/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529408 | 1.00 | TAAR1 (0.61) | TAAR1HTR7MAOAMAOBCYP19A1 | |
| SCHEMBL4633328 | 0.89 | MAOA (0.55) | TAAR1HTR7MAOAMAOBCYP19A1 | |
| SCHEMBL10647922 | 0.82 | MAOA (0.57) | MAOAMAOBCYP19A1SIGMAR1HTR1A | |
| SCHEMBL29943821 | 0.81 | MAOA (0.55) | MAOAMAOBCYP19A1SIGMAR1HTR1A | |
| SCHEMBL249429 | 0.81 | MAOA (0.55) | MAOAMAOBCYP19A1SIGMAR1HTR1A | |
| SCHEMBL29436994 | 0.80 | MAOB (0.86) | MAOAMAOBCYP19A1SIGMAR1 | |
| SCHEMBL2154372 | 0.80 | MAOB (0.86) | MAOAMAOBCYP19A1SIGMAR1 | |
| SCHEMBL7258350 | 0.79 | HTR6 (0.56) | TAAR1HTR7HTR1AACHEAOC3 | |
| SCHEMBL10555327 | 0.79 | DRD2 (0.65) | MAOAMAOBCYP19A1SIGMAR1 | |
| SCHEMBL10554544 | 0.79 | MAOA (0.53) | TAAR1HTR7MAOAMAOBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |