Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450268 | 0.85 | KDM4E (0.50) | KDM4ENPC1RAB9AHSD17B10CASP3 | |
| SCHEMBL15387043 | 0.83 | KDM4E (0.49) | KDM4ENPC1RAB9AHSD17B10CASP3 | |
| SCHEMBL16305428 | 0.81 | SIRT2 (0.55) | KDM4ENPC1RAB9AHSD17B10CASP3 | |
| SCHEMBL175535 | 0.81 | KDM4E (0.56) | KDM4ENPC1RAB9AHSD17B10SIRT2 | |
| SCHEMBL39964 | 0.81 | KDM4E (0.52) | KDM4EHSD17B10PARP1ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL28498072 | 0.80 | FFAR4 (0.55) | KDM4ENPC1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL29623796 | 0.80 | KDM4E (0.47) | KDM4ENPC1RAB9AHSD17B10CASP3 | |
| Hydrochloric Acid SCHEMBL4562961 | 0.79 | PARP1 (0.50) | KDM4EHSD17B10PARP1ALDH1A1TDP1 | |
| SCHEMBL530858 | 0.79 | KEAP1 (0.59) | KDM4EHSD17B10SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL29623849 | 0.78 | BTK (0.57) | KDM4ENPC1RAB9AHSD17B10CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034537-A1 | FLUOROALKOXYALKYLENE-DIHYDROIMIDAZO[5,1-D]TETRAZINONE COMPOUNDS AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | MODIFI BIOSCIENCES, INC. (US) | 2025-02-13 | — | — | WO | disclosed |