Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073788 | 0.84 | NPC1 (0.53) | KDM4EHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL3441356 | 0.84 | AGTR1 (0.54) | KDM4EMKNK1MKNK2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5389527 | 0.82 | AGTR1 (0.53) | KDM4EMKNK1MKNK2ALDH1A1HPGD | |
| SCHEMBL13450268 | 0.80 | KDM4E (0.50) | KDM4EPARP1HSD17B10ALDH1A1HPGD | |
| SCHEMBL31481384 | 0.80 | KDM4E (0.50) | KDM4EPARP1HSD17B10ALDH1A1HPGD | |
| SCHEMBL29623849 | 0.80 | BTK (0.57) | KDM4EHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL15387043 | 0.79 | KDM4E (0.49) | KDM4EPARP1HSD17B10ALDH1A1HPGD | |
| Formic Acid SCHEMBL5388605 | 0.78 | MEN1 (0.49) | KDM4EMKNK1MKNK2HSD17B10ALDH1A1 | |
| SCHEMBL7868859 | 0.78 | MEN1 (0.40) | KDM4EHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL7259307 | 0.78 | FABP4 (0.54) | MKNK1MKNK2MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024516-B | Double-target PARP/EZH2 inhibitor, preparation method and application | 中国药科大学 | 2022-05-17 | — | — | CN | disclosed |