Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16793840 | 0.88 | NPC1 (0.39) | PLAUKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29277569 | 0.84 | TSHR (0.36) | GPR35PLAUKMT2AMEN1NPC1 | |
| SCHEMBL30713271 | 0.84 | TSHR (0.36) | GPR35PLAUKMT2AMEN1NPC1 | |
| SCHEMBL30357636 | 0.81 | GPR35 (0.49) | GPR35NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL27389799 | 0.81 | GPR35 (0.49) | GPR35NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL30162902 | 0.76 | AAK1 (0.45) | KDM4EPOLB | |
| SCHEMBL16809853 | 0.76 | AAK1 (0.45) | KDM4EPOLB | |
| SCHEMBL16540928 | 0.76 | GLA (0.40) | PLAUKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27956166 | 0.76 | AGBL2 (0.44) | PLAUKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL14331014 | 0.75 | PLAU (0.40) | PLAUKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025035108-A2 | INHIBITORS OF PARG | ARASE THERAPEUTICS INC. (US) | 2025-02-13 | — | — | WO | disclosed |