Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277569 | 1.00 | TSHR (0.36) | TSHRHPGDNPC1RAB9ALMNA | |
| SCHEMBL27389799 | 0.88 | GPR35 (0.49) | TSHRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30357636 | 0.88 | GPR35 (0.49) | TSHRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31481925 | 0.84 | GPR35 (0.38) | TSHRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16793840 | 0.81 | NPC1 (0.39) | TSHRNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL16809853 | 0.78 | AAK1 (0.45) | LMNAKDM4E | |
| SCHEMBL30162902 | 0.78 | AAK1 (0.45) | LMNAKDM4E | |
| SCHEMBL18335081 | 0.77 | LMNA (0.41) | TSHRHPGDNPC1RAB9ALMNA | |
| SCHEMBL29277634 | 0.72 | SMN1; SMN2 (0.41) | TSHRNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30713233 | 0.72 | SMN1; SMN2 (0.41) | TSHRNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304183-A | Five-membered and six-membered nitrogen-containing compound, intermediate thereof, preparation method and application | 杭州圣域生物医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |