Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512219 | 1.00 | MAPT (0.57) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL3515437 | 0.87 | HCAR3 (0.52) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL4090213 | 0.87 | HCAR3 (0.61) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL1283854 | 0.84 | MAPT (0.54) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL990451 | 0.83 | MAPT (0.60) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL17845498 | 0.82 | ATM (0.51) | MAPTMAPK1ALDH1A1TDP1ATM | |
| SCHEMBL15322458 | 0.82 | TDP1 (0.51) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL30532042 | 0.82 | ATM (0.51) | MAPTMAPK1ALDH1A1TDP1ATM | |
| SCHEMBL981242 | 0.81 | KAT2B (0.64) | MAPTMAPK1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL12210037 | 0.81 | LMNA (0.50) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025035108-A2 | INHIBITORS OF PARG | ARASE THERAPEUTICS INC. (US) | 2025-02-13 | — | — | WO | disclosed |