Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.52 |
| ▸ | PI4KA | P42356 | 4/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.52 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483001 | 0.79 | PIK3CG (0.63) | PIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL31483065 | 0.78 | PIK3CD (0.53) | PIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL29903062 | 0.77 | JAK2 (0.57) | PIK3CAPIK3CGPIK3CDPIK3CBPI4KA | |
| SCHEMBL31483117 | 0.75 | PIK3CD (0.51) | PIK3CAPIK3CGPIK3CDPIK3CBKCNH2 | |
| SCHEMBL31483046 | 0.73 | PIK3CD (0.53) | PIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL9966497 | 0.72 | MKNK1 (0.57) | PIK3CAPIK3CGPIK3CDPIK3CBPI4KA | |
| SCHEMBL13633547 | 0.72 | DYRK1A (0.63) | PIK3CAPIK3CGPIK3CDPIK3CBPI4KA | |
| SCHEMBL31483081 | 0.72 | PIK3CD (0.70) | PIK3CAPIK3CGPIK3CDPIK3CBPI4KA | |
| SCHEMBL31174412 | 0.72 | CYP2A6 (0.68) | PIK3CAPIK3CGPIK3CDPIK3CBPI4KA | |
| SCHEMBL3754419 | 0.72 | CYP2A6 (0.68) | PIK3CAPIK3CGPIK3CDPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |