Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25056999 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDLMNAHTTHSD17B10 | |
| SCHEMBL31483042 | 0.79 | CYP1A2 (0.51) | ALDH1A1HPGDFDPSHTTNPC1 | |
| SCHEMBL20964586 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAHTTRECQL | |
| SCHEMBL8288041 | 0.75 | KMT2A (0.67) | ALDH1A1HPGDLMNAHTTKDM4E | |
| SCHEMBL3641337 | 0.74 | P2RX7 (0.45) | ALDH1A1P2RX7HPGDRECQLKDM4E | |
| SCHEMBL867510 | 0.73 | BCHE (0.52) | ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL17234481 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDFDPSLMNAHTT | |
| SCHEMBL6865308 | 0.71 | ALDH1A1 (0.73) | ALDH1A1HPGD | |
| SCHEMBL175234 | 0.71 | TDP1 (0.46) | ALDH1A1HPGDLMNARECQLKDM4E | |
| SCHEMBL5841015 | 0.71 | EPHX1 (0.51) | ALDH1A1HSD17B10HDAC1POLBMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |