SCHEMBL31483042

SCHEMBL31483042

NC(=O)NCCNc1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.51
CYP2C19 P33261 1/20 0.50
GAA P10253 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
PKM P14618 1/20 0.49
CXCR4 P61073 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGAV P06756 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
FDPS P14324 1/20 0.46
FABP1 P07148 1/20 0.46
FABP6 P51161 1/20 0.46
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
CYP2D6 P10635 1/20 0.44
NOS1 P29475 1/20 0.43
ALOX12 P18054 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10401970 0.85 CYP1A2 (0.53) CYP1A2CYP2C19GAANPC1RAB9A
SCHEMBL10401969 0.85 CYP2C19 (0.56) CYP1A2CYP2C19GAANPC1RAB9A
SCHEMBL8145501 0.83 CYP1A2 (0.56) CYP1A2CYP2C19GAANPC1RAB9A
SCHEMBL3265804 0.82 CYP1A2 (0.70) CYP1A2CYP2C19GAANPC1RAB9A
SCHEMBL6302594 0.81 CYP1A2 (0.53) CYP1A2CYP2C19GAANPC1RAB9A
SCHEMBL30975230 0.81 KMT2A (0.68) SMN1; SMN2ALDH1A1
SCHEMBL31483040 0.79 ALDH1A1 (0.61) NPC1RAB9AHTTFDPSALDH1A1
SCHEMBL5845136 0.78 ITGB3 (0.55) CYP1A2CYP2C19GAANPC1RAB9A
SCHEMBL1837886 0.78 CYP1A2 (0.66) CYP1A2CYP2C19GAANPC1RAB9A
SCHEMBL2857962 0.77 GAA (0.55) CYP1A2CYP2C19GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841829-A Compounds for the treatment of PI3K gamma mediated diseases and uses thereof 中国科学院合肥物质科学研究院 2025-04-18 CN disclosed