Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905029 | 0.72 | PIK3CG (0.52) | PIK3CAPIK3CGMTORPDGFRBPDGFRA | |
| SCHEMBL14395105 | 0.72 | LOXL2 (0.57) | PIK3CAPIK3CGPIK3CDPDGFRBPDGFRA | |
| SCHEMBL23905206 | 0.70 | ERN1 (0.52) | PIK3CAPIK3CGPDGFRBPDGFRAEGFR | |
| SCHEMBL4527415 | 0.70 | PDGFRB (0.51) | PDGFRBPDGFRACHEK1 | |
| SCHEMBL5183178 | 0.70 | PDGFRB (0.59) | PIK3CAPIK3CGMTORPDGFRBPDGFRA | |
| SCHEMBL17016700 | 0.70 | PDGFRB (0.59) | PIK3CAPIK3CGPIK3CDMTORPDGFRB | |
| SCHEMBL30174540 | 0.70 | NPC1 (0.63) | PLAUHTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL216242 | 0.70 | NPC1 (0.63) | PLAUHTR3EHTR3BHTR3ABACE1 | |
| SCHEMBL11712219 | 0.70 | ALDH1A1 (0.58) | PIK3CAPLAUHTR3EHTR3BHTR3A | |
| SCHEMBL23905079 | 0.69 | PIK3CG (0.49) | PIK3CAPIK3CGPIK3CDMTORPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |