Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264491 | 0.85 | MTNR1A (0.71) | MTNR1AMTNR1BMAPT | |
| SCHEMBL2187414 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BF10POLBMAPT | |
| SCHEMBL17277318 | 0.82 | POLB (0.68) | MTNR1AMTNR1BPOLBHPGDSMN1; SMN2 | |
| SCHEMBL19513497 | 0.82 | DRD2 (0.56) | MTNR1AMTNR1BF10SMN1; SMN2 | |
| SCHEMBL31483051 | 0.81 | SMN1; SMN2 (0.53) | MTNR1AMTNR1BMAPTNPC1RAB9A | |
| SCHEMBL1053081 | 0.80 | MTNR1A (0.69) | MTNR1AMTNR1BF10POLBNPC1 | |
| SCHEMBL23067913 | 0.79 | DRD2 (0.55) | — | |
| SCHEMBL30756654 | 0.79 | DRD2 (0.55) | — | |
| SCHEMBL12062132 | 0.78 | POLB (0.54) | MTNR1AMTNR1BF10POLBMAPT | |
| SCHEMBL7569065 | 0.78 | KDM4E (0.48) | F10POLBMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |