Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HAT1 | O14929 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30600853 | 0.91 | NPC1 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL9776 | 0.81 | MEN1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL21246174 | 0.81 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL4662749 | 0.76 | MEN1 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL28856739 | 0.74 | RXRA (0.47) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL23932729 | 0.74 | MEN1 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL23610743 | 0.74 | NPC1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL23610744 | 0.74 | NPC1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL3327111 | 0.73 | JAK2 (0.40) | SMN1; SMN2ALDH1A1L3MBTL1HTTMEN1 | |
| SCHEMBL31483066 | 0.73 | CYP2A6 (0.40) | SMN1; SMN2ALDH1A1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |