SCHEMBL31483205

SCHEMBL31483205

CC(=O)c1sc(C)nc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.42
ALDH1A1 P00352 5/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 1/20 0.39
KMT2A Q03164 2/20 0.38
RXFP1 Q9HBX9 3/20 0.37
NPC1 O15118 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 3/20 0.36
MEN1 O00255 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP1A2 P05177 1/20 0.36
GAA P10253 1/20 0.36
CYP2C9 P11712 1/20 0.36
DHODH Q02127 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
RECQL P46063 1/20 0.35
AMY1A P0DUB6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8964642 0.83 ALDH1A1 (0.53) RAB9AALDH1A1HPGDTSHRRXFP1
SCHEMBL9459998 0.81 POLB (0.40) RAB9AALDH1A1HPGDTSHRNPC1
SCHEMBL13674670 0.78 MAPT (0.44) RAB9AALDH1A1HPGDTSHRKMT2A
SCHEMBL211358 0.77 RXFP1 (0.50) RAB9AALDH1A1HPGDTSHRKMT2A
Bromide SCHEMBL6121613 0.76 SMN1; SMN2 (0.49) RAB9AALDH1A1HPGDTSHRKMT2A
SCHEMBL15182526 0.74 L3MBTL1 (0.44) RAB9AALDH1A1HPGDKMT2ARXFP1
Bromide SCHEMBL10980464 0.72 L3MBTL1 (0.42) RAB9AALDH1A1HPGDKMT2ARXFP1
SCHEMBL1432390 0.72 ALDH1A1 (0.38) RAB9AALDH1A1HPGDTSHRRXFP1
SCHEMBL31483213 0.71 MAPT (0.50) RAB9AALDH1A1HPGDKMT2ANPC1
SCHEMBL15651992 0.71 SMN1; SMN2 (0.36) RAB9AALDH1A1HPGDRXFP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072673-A1 THIAZOLE DERIVATIVES AND THEIR USE AS IRE 1 INHIBITORS AL22.02.01, INC. (US) 2025-04-03 WO disclosed