Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484402 | 0.84 | NPC1 (0.34) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31484416 | 0.74 | MEN1 (0.39) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL31271045 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9838258 | 0.72 | MAPT (0.47) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9836921 | 0.72 | MAPT (0.36) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31484430 | 0.70 | KDM4E (0.50) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL12314708 | 0.69 | TDP1 (0.50) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL10480000 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1MAPTCYP3A4TSHR | |
| SCHEMBL761929 | 0.66 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL31484441 | 0.66 | LMNA (0.39) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431381-A | Heterocyclic compounds and application thereof | 上海艾力斯医药科技股份有限公司 | 2025-02-14 | — | — | CN | disclosed |