SCHEMBL31484547

SCHEMBL31484547

N#Cc1c(-n2c3ccccc3c3ccccc32)cc(-n2c3ccccc3c3ccccc32)c(-n2c3ccccc3c3ccccc32)c1-c1ccncc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 4/20 0.37
CYP11B2 P19099 1/20 0.37
SQOR Q9Y6N5 1/20 0.36
NRP1 O14786 1/20 0.36
PDE9A O76083 1/20 0.36
PDE1C Q14123 1/20 0.36
ADORA1 P30542 3/20 0.35
ADORA2A P29274 2/20 0.35
KDM4E B2RXH2 3/20 0.33
GLA P06280 1/20 0.33
PIM1 P11309 1/20 0.33
RUNX1 Q01196 1/20 0.33
CBFB Q13951 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR3A P46098 1/20 0.33
MET P08581 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
EGFR P00533 1/20 0.32
RAF1 P04049 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31484576 0.88 MEN1 (0.47) MAPK14CYP11B2SQORADORA2AKDM4E
SCHEMBL31484545 0.87 ADORA1 (0.37) MAPK14SQORNRP1PDE9APDE1C
SCHEMBL31272858 0.84 MAPK14 (0.40) MAPK14CYP11B2SQORNRP1PDE9A
SCHEMBL23343971 0.82 MAPK14 (0.36) MAPK14CYP11B2SQORADORA1ADORA2A
SCHEMBL19908983 0.82 CYP11B2 (0.41) MAPK14CYP11B2SQORNRP1ADORA1
SCHEMBL31273507 0.82 CYP11B2 (0.41) MAPK14CYP11B2SQORNRP1ADORA1
SCHEMBL20763412 0.82 CYP11B2 (0.41) MAPK14CYP11B2SQORNRP1PDE9A
SCHEMBL31484641 0.82 KIF11 (0.36) ADORA2AKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL31663618 0.82 CYP11B2 (0.36) CYP11B2PDE9APDE1CADORA2AKDM4E
SCHEMBL13921553 0.81 PDE9A (0.44) CYP11B2PDE9APDE1CKDM4EHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899174-A Synthesis process of pyridine carbazole compound 南京师范大学 2025-04-29 CN disclosed