SCHEMBL31484576

SCHEMBL31484576

COc1ccc2c3ccccc3n(-c3cc(-n4c5ccccc5c5ccc(OC)cc54)c(-n4c5ccccc5c5ccc(OC)cc54)c(-c4ccncc4)c3C#N)c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
MAPT P10636 4/20 0.47
KDM4E B2RXH2 3/20 0.47
HTT P42858 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
LMNA P02545 1/20 0.47
PABPC1 P11940 1/20 0.47
MAPK1 P28482 1/20 0.47
CASP3 P42574 1/20 0.47
NCOA1 Q15788 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
ADORA2A P29274 1/20 0.43
SQOR Q9Y6N5 2/20 0.39
MAPK14 Q16539 6/20 0.37
MAPK13 O15264 5/20 0.37
MAPK12 P53778 5/20 0.37
MAPK11 Q15759 5/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31484547 0.88 MAPK14 (0.37) MEN1KMT2AKDM4EMAPK1ADORA2A
SCHEMBL31484545 0.77 ADORA1 (0.37) MEN1KMT2AADORA2ASQORMAPK14
SCHEMBL31484565 0.77 KDM4E (0.56) MEN1KMT2AMAPTKDM4EHTT
SCHEMBL20923665 0.76 SQOR (0.41) MEN1KMT2AMAPTKDM4EHTT
SCHEMBL31484641 0.75 KIF11 (0.36) KDM4ELMNAMAPK1ADORA2AALDH1A1
SCHEMBL31272858 0.74 MAPK14 (0.40) MEN1KMT2AKDM4EADORA2ASQOR
SCHEMBL31273173 0.73 SQOR (0.36) MEN1KMT2AKDM4EMAPK1ADORA2A
SCHEMBL23343971 0.73 MAPK14 (0.36) MAPTKDM4EADORA2ASQORMAPK14
SCHEMBL31273507 0.73 CYP11B2 (0.41) MEN1KMT2AKDM4EL3MBTL1NCOA3
SCHEMBL19908983 0.73 CYP11B2 (0.41) MEN1KMT2AKDM4EL3MBTL1NCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899174-A Synthesis process of pyridine carbazole compound 南京师范大学 2025-04-29 CN disclosed