Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236259 | 0.90 | GPR119 (0.52) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL21360338 | 0.90 | GPR119 (0.52) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL21360343 | 0.88 | GPR119 (0.50) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL12089736 | 0.87 | GPR119 (0.40) | GPR119PARP1 | |
| SCHEMBL12336485 | 0.86 | ALDH1A1 (0.46) | GPR119KDM4EUSP30STSPARP1 | |
| SCHEMBL14932381 | 0.86 | GPR119 (0.57) | GPR119CKS1BSKP1SKP2NAMPT | |
| SCHEMBL38665341 | 0.86 | USP30 (0.43) | GPR119USP30SMARCA2SMARCA4PBRM1 | |
| SCHEMBL21360342 | 0.86 | GPR119 (0.48) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL21360375 | 0.83 | GPR119 (0.55) | GPR119JAK2JAK1KDM4EPKM | |
| SCHEMBL20129676 | 0.83 | GPR119 (0.55) | GPR119USP30SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775260-A | Pyrimidine-2, 4 (1H, 3H) -dione compounds, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2025-04-08 | — | — | CN | disclosed |