Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575335 | 0.85 | KDM1A (0.38) | ICMTDGAT1RORC | |
| SCHEMBL29431223 | 0.84 | AKR1B1 (0.42) | CCR6HKDC1PTPN1MEN1RAD52 | |
| SCHEMBL22775478 | 0.84 | AKR1B1 (0.42) | CCR6HKDC1PTPN1MEN1RAD52 | |
| SCHEMBL4314806 | 0.81 | KIF11 (0.36) | CA2ICMTDGAT1RORCCA12 | |
| SCHEMBL16005219 | 0.79 | DGAT1 (0.36) | CA2ICMTDGAT1RORCCA12 | |
| SCHEMBL31463372 | 0.78 | CCR6 (0.46) | CCR6HKDC1MEN1RECQLKMT2A | |
| SCHEMBL29819673 | 0.77 | HDAC1 (0.40) | CA2ICMTRORC | |
| SCHEMBL12984764 | 0.77 | HDAC1 (0.40) | CA2ICMTRORC | |
| SCHEMBL31551664 | 0.73 | DGAT1 (0.55) | MEN1KMT2ADGAT1HSD17B10 | |
| SCHEMBL12473692 | 0.73 | DGAT1 (0.50) | MEN1KMT2AGAAICMTDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114616226-B | Pyridine derivatives as TMEM16A modulators for the treatment of respiratory disorders | TMEM16A有限公司 | 2025-03-04 | — | — | CN | disclosed |