SCHEMBL31486514

SCHEMBL31486514

Cc1cc2nc(C#N)oc2cc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 4/20 0.54
PSMB5 P28074 2/20 0.54
KDM4E B2RXH2 8/20 0.35
ALDH1A1 P00352 6/20 0.35
HSD17B10 Q99714 5/20 0.35
NPC1 O15118 5/20 0.35
RAB9A P51151 5/20 0.35
SMN1; SMN2 Q16637 5/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 5/20 0.33
F2RL3 Q96RI0 4/20 0.33
HPGD P15428 4/20 0.33
NQO2 P16083 1/20 0.33
CEPT1 Q9Y6K0 1/20 0.32
TP53 P04637 2/20 0.32
ALOX15 P16050 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
GAA P10253 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9797527 0.86 PSMB8 (0.63) PSMB8PSMB5MAPTALOX15LMNA
SCHEMBL9797235 0.84 PSMB8 (0.61) PSMB8PSMB5MAPTALOX15LMNA
SCHEMBL31486637 0.74 MAPT (0.42) KDM4EALDH1A1HSD17B10NPC1RAB9A
SCHEMBL10808996 0.74 MAPT (0.42) KDM4EALDH1A1HSD17B10NPC1RAB9A
SCHEMBL15834786 0.74 MAPT (0.50) KDM4EALDH1A1HSD17B10NPC1RAB9A
SCHEMBL31486630 0.73 L3MBTL1 (0.48) KDM4EALDH1A1HSD17B10NPC1RAB9A
SCHEMBL862784 0.73 L3MBTL1 (0.48) KDM4EALDH1A1HSD17B10NPC1RAB9A
SCHEMBL21689039 0.70 PSMB8 (0.65) PSMB8PSMB5KDM4EALDH1A1HSD17B10
SCHEMBL28024375 0.70 PSMB8 (0.65) PSMB8PSMB5KDM4EMAPTF2RL3
SCHEMBL9757128 0.70 PSMB8 (0.65) PSMB8PSMB5NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250135059-A1 COMPOSITIONS COMPRISING FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY 2025-05-01 US disclosed