Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FABP6 | P51161 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561724 | 0.84 | MAPT (0.44) | MAPTNUDT1LMNACYP1A2THRB | |
| SCHEMBL862784 | 0.77 | L3MBTL1 (0.48) | MAPTLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31486630 | 0.77 | L3MBTL1 (0.48) | MAPTLMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31119200 | 0.75 | MAPT (0.61) | MAPTNUDT1LMNACYP1A2THRB | |
| SCHEMBL12261 | 0.75 | MAPT (0.61) | MAPTNUDT1LMNACYP1A2THRB | |
| SCHEMBL557792 | 0.75 | PIK3CG (0.61) | MAPTNUDT1LMNACYP1A2THRB | |
| SCHEMBL6738898 | 0.74 | ALDH1A1 (0.41) | MAPTLMNACYP1A2THRBALOX15 | |
| SCHEMBL10981532 | 0.74 | MAPT (0.60) | MAPTNUDT1LMNACYP1A2THRB | |
| SCHEMBL19270393 | 0.74 | PIK3CG (0.46) | MAPTNUDT1LMNACYP1A2THRB | |
| SCHEMBL31486514 | 0.74 | PSMB8 (0.54) | MAPTLMNAALOX15SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113768935-A | Prophylactic and/or therapeutic agent for immune diseases | 大鹏药品工业株式会社 | 2021-12-10 | — | — | CN | disclosed |
| CN-107206001-B | Prophylactic and/or therapeutic agent for immune diseases | 大鹏药品工业株式会社 | 2021-09-28 | — | — | CN | disclosed |
| EP-3120852-B1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR IMMUNE DISEASES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2019-05-01 | — | — | EP | disclosed |
| US-9951032-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-04-24 | — | — | US | disclosed |
| US-9951032-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2018-04-24 | — | — | US | disclosed |
| EP-2947086-B1 | NOVEL FUSED PYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-20170369457-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2017-12-28 | — | — | US | disclosed |
| EP-2934498-B1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-11-15 | — | — | EP | disclosed |
| US-9782412-B2 | Preventive and/or therapeutic agent of immune disease | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2017-10-10 | — | — | US | disclosed |
| US-9758497-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2017-09-12 | — | — | US | disclosed |
| EP-3120852-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR IMMUNE DISEASES | Taiho Pharmaceutical Co., Ltd. (JP) | 2017-01-25 | — | — | EP | disclosed |
| US-20160347728-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-12-01 | — | — | US | disclosed |
| US-20160347728-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-12-01 | — | — | US | disclosed |
| US-9428474-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2016-08-30 | — | — | US | disclosed |
| US-9428474-B2 | Antibacterial compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2016-08-30 | — | — | US | disclosed |
| US-20160115168-A1 | NOVEL FUSED PYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-04-28 | — | — | US | disclosed |
| US-20150344449-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN-CILAG FRANCE (FR) | 2015-12-03 | — | — | US | disclosed |
| US-20150344449-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN-CILAG FRANCE (FR) | 2015-12-03 | — | — | US | disclosed |
| EP-2947086-A1 | NOVEL FUSED PYRIMIDINE COMPOUND OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2015-11-25 | — | — | EP | disclosed |
| WO-2014096300-A2 | ANTIBACTERIAL COMPOUNDS | JANSSEN R&D IRELAND (IE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344449-A1 | ANTIBACTERIAL COMPOUNDS | CLPP, CFTR, ELANE | MAPT 2107/4885NUDT1 348/4885LMNA 4455/4885 |
| US-20170369457-A1 | Antibacterial Compounds | CLPP, CFTR, ELANE | MAPT 2107/4885NUDT1 348/4885LMNA 4455/4885 |
| US-20160347728-A1 | ANTIBACTERIAL COMPOUNDS | CLPP, CFTR, ELANE | MAPT 2107/4885NUDT1 348/4885LMNA 4455/4885 |
| US-20160115168-A1 | NOVEL FUSED PYRIMIDINE COMPOUND OR SALT THEREOF | BTK, JAK2, SYK | MAPT 4777/4885NUDT1 1032/4885LMNA 4508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.