Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21574083 | 0.89 | MEN1 (0.46) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL891527 | 0.83 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL18727653 | 0.83 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL11643325 | 0.83 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL8776387 | 0.82 | RARB (0.44) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL23903751 | 0.80 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL3233226 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1GAAMAPT | |
| Iodide SCHEMBL11792583 | 0.79 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL19232219 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL4304302 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910262-B1 | NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS | FIRMENICH & CIE (CH) | 2010-03-03 | — | — | EP | disclosed |
| US-20080214419-A1 | Naphthalenone Derivative with Powdery-Ionone Type Odors | FIRMENICH SA (CH) | 2008-09-04 | — | — | US | disclosed |
| EP-1910262-A1 | NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS | FIRMENICH SA (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007010420-A1 | NAPHTHALENONE DERIVATIVE WITH POWDERY-IONONE TYPE ODOURS | FIRMENICH SA (CH) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214419-A1 | Naphthalenone Derivative with Powdery-Ionone Type Odors | IPO5, TRPA1, SCN5A | MEN1 1420/4885KMT2A 3025/4885ALDH1A1 1075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.