SCHEMBL31486930

SCHEMBL31486930

O=C(NC1CC2CCCC(C1)N2)c1c2n(c3ccc(F)cc13)CCC2

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 8/20 0.44
GAA P10253 2/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
GRM5 P41594 1/20 0.36
KMT2A Q03164 2/20 0.36
HTR4 Q13639 2/20 0.36
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31486789 0.87 HTR3A (0.54) HTR3AGAAALDH1A1ALOX15
SCHEMBL31487099 0.85 HTR4 (0.47) HTR3AGAAALDH1A1KDM4EHTR4
SCHEMBL31486775 0.85 USP2 (0.48) HTR3AGAAMAPK1
Formic Acid SCHEMBL31487201 0.84 HTR3A (0.51) HTR3AGAAALDH1A1ALOX15
Formic Acid SCHEMBL31486974 0.82 HTR4 (0.44) HTR3AGAAALDH1A1KDM4EHTR4
Formic Acid SCHEMBL31486808 0.82 HTR3A (0.54) HTR3A
Formic Acid SCHEMBL31486902 0.82 HTR3A (0.54) HTR3A
SCHEMBL31486779 0.81 HTR3A (0.54) HTR3A
SCHEMBL31487330 0.74 KMT2A (0.57) GAAMAPK1ALDH1A1KDM4EKMT2A
SCHEMBL31486817 0.74 KMT2A (0.57) GAAMAPK1ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077825-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS FAUNA BIO INCORPORATED (US) 2025-04-17 WO disclosed