Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18764884 | 0.80 | DRD2 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL23588215 | 0.77 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL24841515 | 0.77 | ADRB3 (0.41) | NOTUMADRB3TMEM97HRH3HDAC8 | |
| SCHEMBL21281675 | 0.76 | NOTUM (0.42) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL15199612 | 0.76 | ADRB3 (0.44) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL24841256 | 0.75 | SSTR4 (0.40) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL31728124 | 0.75 | NOTUM (0.43) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL22319717 | 0.74 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL4784720 | 0.73 | NOTUM (0.46) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL7464070 | 0.73 | ADRB3 (0.46) | NOTUMADRB3TMEM97HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025058977-A1 | MODULATORS OF CORONAVIRUS 3C-LIKE PROTEASE AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2025-03-20 | — | — | WO | disclosed |