Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.35 |
| ▸ | SIK1 | P57059 | 1/20 | 0.35 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.35 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464070 | 0.86 | ADRB3 (0.46) | NOTUMADRB3TMEM97HRH3POLB | |
| SCHEMBL22040159 | 0.84 | JMJD6 (0.45) | HTTALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4672515 | 0.84 | NOTUM (0.44) | NOTUMADRB3TMEM97HRH3POLB | |
| SCHEMBL15199612 | 0.83 | ADRB3 (0.44) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL29224325 | 0.82 | ADRB3 (0.44) | NOTUMADRB3TMEM97HRH3POLB | |
| SCHEMBL31728124 | 0.81 | NOTUM (0.43) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL23588215 | 0.81 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL6854963 | 0.81 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL18366836 | 0.81 | ADRB3 (0.41) | NOTUMADRB3TMEM97HRH3POLB | |
| SCHEMBL21202361 | 0.80 | NOTUM (0.42) | NOTUMADRB3TMEM97HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| CN-116082254-B | Preparation method of 1-alkyl-1, 2, 4-triazole-3-methanol | 浙江永太科技股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-116082254-A | Preparation method of 1-alkyl-1, 2, 4-triazole-3-methanol | 浙江永太科技股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-20230121730-A1 | OXADIAZOLINE COMPOUNDS OR SALTS THEREOF, AGROHORTICULTURAL FUNGICIDES CONTAINING THE COMPOUNDS, AND METHODS OF USING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 2023-04-20 | — | — | US | disclosed |
| US-11066399-B2 | Ferroportin inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2021-07-20 | — | — | US | disclosed |
| US-20210139472-A1 | Novel Ferroportin Inhibitors | VIFOR (INTERNATIONAL) AG (CH) | 2021-05-13 | — | — | US | disclosed |
| WO-2008074991-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008074991-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139472-A1 | Novel Ferroportin Inhibitors | HAMP, SLC40A1, HMOX1 | NOTUM 2730/4885ADRB3 2996/4885TMEM97 705/4885 |
| US-20230121730-A1 | OXADIAZOLINE COMPOUNDS OR SALTS THEREOF, AGROHORTICULTURAL FUNGICIDES CONTAINING THE COMPOUNDS, AND METHODS OF USING THE SAME | CBR3, XDH, OXA1L | NOTUM 464/4885ADRB3 1829/4885TMEM97 4248/4885 |
| US-11066399-B2 | Ferroportin inhibitors | HAMP, SLC40A1, FTH1 | NOTUM 2679/4885ADRB3 2627/4885TMEM97 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.