Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GLA | P06280 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.36 |
| ▸ | CASP7 | P55210 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854963 | 0.86 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL15199612 | 0.85 | ADRB3 (0.44) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL24842047 | 0.85 | ADRB3 (0.40) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL6853830 | 0.85 | NOTUM (0.39) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL4672515 | 0.83 | NOTUM (0.44) | NOTUMADRB3TMEM97HRH3SMN1; SMN2 | |
| SCHEMBL6855523 | 0.83 | TSHR (0.39) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL21281675 | 0.83 | NOTUM (0.42) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL4784720 | 0.81 | NOTUM (0.46) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL7464070 | 0.81 | ADRB3 (0.46) | NOTUMADRB3TMEM97HRH3SMN1; SMN2 | |
| SCHEMBL24841515 | 0.80 | ADRB3 (0.41) | NOTUMADRB3TMEM97HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |