SCHEMBL3148771

SCHEMBL3148771

CC(=O)C(C(=O)O)C(=O)CCl

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
GRIK1 P39086 1/20 0.31
SLC7A5 Q01650 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3871245 0.87 TSHR (0.35) TSHR
SCHEMBL9622059 0.84 TSHR (0.44) TSHRLMNA
SCHEMBL1930965 0.77 TDP1 (0.38) GRIK1SLC7A5
SCHEMBL27731214 0.75 KDM4E (0.36) GRIK1SLC7A5LMNA
SCHEMBL28523 0.74 FFAR3 (0.43) TSHRSLC7A5LMNA
SCHEMBL269877 0.74 FFAR3 (0.43) TSHRSLC7A5LMNA
SCHEMBL1318841 0.73 HDAC1 (0.42) TSHRGRIK1
SCHEMBL8525838 0.73 LMNA (0.46) GRIK1LMNA
SCHEMBL31463485 0.73 ALDH1A1 (0.31)
SCHEMBL4983762 0.73 ALDH1A1 (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100081839-A1 PROCESS FOR PREPARATION OF CRYSTALLINE CLOPIDOGREL HYDROGEN SULPHATE FORM I IPCA LABORATORIES LTD. (IN) 2010-04-01 US disclosed
EP-2114957-A2 PROCESS FOR PREPARATION OF CRYSTALLINE CLOPIDOGREL HYDROGEN SULPHATE FORM I IPCA Laboratories Limited (IN) 2009-11-11 EP disclosed
US-20080188663-A1 Process for the preparation of crystalline clopidogrel hydrogen sulphate Form I IPCA LABORATORIES LIMITED (IN) 2008-08-07 US disclosed
WO-2008093357-A2 PROCESS FOR PREPARATION OF CRYSTALLINE CLOPIDOGREL HYDROGEN SULPHATE FORM I IPCA LABORATORIES LIMITED (IN) 2008-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100081839-A1 PROCESS FOR PREPARATION OF CRYSTALLINE CLOPIDOGREL HYDROGEN SULPHATE FORM I VKORC1, VKORC1L1, PTGER1 TSHR 3025/4885GRIK1 1383/4885SLC7A5 4177/4885
US-20080188663-A1 Process for the preparation of crystalline clopidogrel hydrogen sulphate Form I CYP2S1, CYP2F1, VKORC1L1 TSHR 4697/4885GRIK1 1992/4885SLC7A5 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.