Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318841 | 0.81 | HDAC1 (0.42) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL6050445 | 0.79 | HDAC1 (0.40) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL1930965 | 0.75 | TDP1 (0.38) | GRIK1SLC1A3SLC1A2SLC1A1GRIA4 | |
| SCHEMBL3148771 | 0.73 | TSHR (0.36) | LMNAGRIK1 | |
| SCHEMBL269877 | 0.73 | FFAR3 (0.43) | LMNAKDM4EFFAR3 | |
| SCHEMBL28523 | 0.73 | FFAR3 (0.43) | LMNAKDM4EFFAR3 | |
| SCHEMBL15657384 | 0.72 | ALDH1A1 (0.56) | LMNASLC15A2 | |
| Succinic Acid SCHEMBL15066279 | 0.70 | TP53 (0.58) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL1986431 | 0.70 | GABRP (0.54) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| SCHEMBL1332607 | 0.70 | GRM8 (0.48) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724560-B1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEM CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0724560-A1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |
| US-5466863-A | 3-OXOADIPATE ESTERS OF POLYOLS WHICH ARE USEFUL AS CROSSLINKERS IN THERMOSETTING COATINGS | EASTMAN CHEMICAL COMPANY (US) | 1995-11-14 | — | — | US | disclosed |
| US-5412151-A | Oxoadipate esters of polyols | EASTMAN CHEMICAL COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| WO-1995011220-A1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1995-04-27 | — | — | WO | disclosed |