Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487947 | 0.83 | MAPT (0.46) | RETTHRBMAPTKDM4EHTT | |
| SCHEMBL21263008 | 0.83 | MEN1 (0.54) | RETTHRBMAPTKDM4EHTT | |
| SCHEMBL31487838 | 0.82 | HTT (0.53) | LMNAMAPTKDM4EHTT | |
| SCHEMBL21247961 | 0.81 | TP53 (0.47) | RETTHRBMAPT | |
| SCHEMBL21247887 | 0.80 | TP53 (0.56) | — | |
| SCHEMBL21248566 | 0.80 | LMNA (0.48) | LMNA | |
| SCHEMBL21247862 | 0.80 | TP53 (0.57) | — | |
| SCHEMBL21248402 | 0.80 | LMNA (0.57) | LMNATHRB | |
| SCHEMBL21248018 | 0.80 | TP53 (0.57) | — | |
| SCHEMBL21248037 | 0.78 | TP53 (0.44) | LMNARETTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025089370-A1 | COMPOUNDS AS CSF1R INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-05-01 | — | — | WO | disclosed |