Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487838 | 0.87 | HTT (0.53) | MAPTKDM4EHTTMEN1KMT2A | |
| SCHEMBL29548305 | 0.86 | SPR (0.40) | RETGPR119 | |
| SCHEMBL31487737 | 0.83 | LMNA (0.47) | MAPTTHRBKDM4EHTTRET | |
| SCHEMBL31487545 | 0.83 | MEN1 (0.45) | MAPTTHRBKDM4EHTTMEN1 | |
| SCHEMBL31488149 | 0.78 | MEN1 (0.54) | MAPTTHRBMEN1KMT2AUSP2 | |
| SCHEMBL31487750 | 0.78 | ALDH1A1 (0.53) | MAPTKDM4EHTTMEN1KMT2A | |
| SCHEMBL21263008 | 0.78 | MEN1 (0.54) | MAPTTHRBKDM4EHTTMEN1 | |
| SCHEMBL31487835 | 0.78 | GPR119 (0.53) | MEN1KMT2AUSP2HPGDNPSR1 | |
| SCHEMBL17398401 | 0.77 | KDM4E (0.53) | MAPTTHRBKDM4EHTTKMT2A | |
| SCHEMBL1979040 | 0.77 | KDM4E (0.53) | MAPTTHRBKDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025089370-A1 | COMPOUNDS AS CSF1R INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-05-01 | — | — | WO | disclosed |