Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487947 | 0.87 | MAPT (0.46) | HTTMEN1KMT2AMAPTKDM4E | |
| SCHEMBL31487750 | 0.85 | ALDH1A1 (0.53) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31487737 | 0.82 | LMNA (0.47) | HTTMAPTLMNAKDM4E | |
| SCHEMBL21404006 | 0.80 | MEN1 (0.63) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3545326 | 0.80 | ALDH1A1 (0.57) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12491802 | 0.79 | ALDH1A1 (0.56) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1529099 | 0.79 | ALDH1A1 (0.56) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24954125 | 0.78 | ALDH1A1 (0.55) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL15156769 | 0.77 | ALDH1A1 (0.54) | HTTMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31487545 | 0.77 | MEN1 (0.45) | HTTMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025089370-A1 | COMPOUNDS AS CSF1R INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-05-01 | — | — | WO | disclosed |