SCHEMBL31487816

SCHEMBL31487816

CC(C)(C)OC(=O)N1CCC(c2cnn3cc(OS(=O)(=O)C(F)(F)F)cnc23)CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 8/20 0.45
▸ CYP3A4 P08684 1/20 0.41
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ USP2 O75604 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ NPSR1 Q6W5P4 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ HPGDS O60760 1/20 0.40
▸ POLB P06746 1/20 0.39
▸ JAK2 O60674 1/20 0.39
▸ JAK1 P23458 1/20 0.39
▸ TYK2 P29597 1/20 0.39
▸ JAK3 P52333 1/20 0.39
▸ DDB1 Q16531 1/20 0.39
▸ CRBN Q96SW2 1/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488043 0.87 GPR119 (0.34) GPR119
SCHEMBL31487869 0.85 GPR119 (0.44) GPR119MEN1KMT2AUSP2HPGD
SCHEMBL31487807 0.83 GPR119 (0.44) GPR119MEN1KMT2AUSP2HPGD
SCHEMBL31487820 0.82 RET (0.47) GPR119MEN1KMT2AHPGDKDM4E
SCHEMBL31487760 0.81 GPR119 (0.47) GPR119MEN1KMT2AUSP2HPGD
SCHEMBL31487766 0.81 GPR119 (0.48) GPR119MEN1KMT2AUSP2HPGD
SCHEMBL31487843 0.78 RET (0.55) GPR119HPGDS
SCHEMBL31487734 0.76 GPR119 (0.52) GPR119HPGDSJAK2JAK1TYK2
SCHEMBL31487895 0.76 DDB1 (0.47) GPR119HPGDSJAK2JAK3DDB1
SCHEMBL19103505 0.75 NAMPT (0.53) GPR119DDB1CRBNKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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