SCHEMBL31487807

SCHEMBL31487807

CC(C)(C)OC(=O)N1CCC(c2cnn3cc(OCC(F)F)cnc23)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 5/20 0.44
▸ ALOX5AP P20292 2/20 0.42
▸ FEN1 P39748 2/20 0.42
▸ RET P07949 2/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ THRB P10828 1/20 0.40
▸ NR3C1 P04150 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ USP2 O75604 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487769 0.86 ALOX5AP (0.44) GPR119ALOX5APFEN1RETKDM4E
SCHEMBL31487820 0.86 RET (0.47) GPR119RETKDM4ENR3C1MEN1
SCHEMBL31487816 0.83 GPR119 (0.45) GPR119KDM4EMAPTTHRBMEN1
SCHEMBL31487760 0.82 GPR119 (0.47) GPR119RETKDM4EMAPTTHRB
SCHEMBL31487766 0.81 GPR119 (0.48) GPR119RETKDM4EMAPTTHRB
SCHEMBL31487843 0.79 RET (0.55) GPR119RET
SCHEMBL31487895 0.77 DDB1 (0.47) GPR119RET
SCHEMBL31487734 0.77 GPR119 (0.52) GPR119RETKDM4EMAPTTHRB
SCHEMBL31487735 0.75 GPR119 (0.54) GPR119RETKDM4EMAPTTHRB
SCHEMBL31487750 0.73 ALDH1A1 (0.53) GPR119KDM4EMAPTMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025089370-A1 COMPOUNDS AS CSF1R INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-01 — — WO disclosed
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