Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372988 | 0.88 | KDM4E (0.37) | KDM4ECYP1A2CYP2C19KMT2AHSD17B10 | |
| SCHEMBL3156036 | 0.86 | ACE (0.41) | CYP1A2CYP2C19CTSSCTSKPYGL | |
| SCHEMBL30852406 | 0.85 | CYP2C19 (0.53) | KDM4ECYP1A2CYP2C19KMT2AHSD17B10 | |
| SCHEMBL29922241 | 0.85 | ALDH1A1 (0.38) | KDM4EKMT2AHSD17B10PYGLMAPT | |
| SCHEMBL27372856 | 0.84 | PYGL (0.39) | HSD17B10PYGLALDH1A1GNPAT | |
| SCHEMBL30852354 | 0.83 | KDM4E (0.40) | KDM4ECYP1A2CYP2C19KMT2AHSD17B10 | |
| SCHEMBL16098526 | 0.83 | GRN (0.38) | KDM4EKMT2AHSD17B10MAPTALDH1A1 | |
| SCHEMBL30852301 | 0.82 | MME (0.40) | KDM4EHSD17B10PYGLALDH1A1LMNA | |
| SCHEMBL27373092 | 0.82 | MME (0.40) | KDM4EHSD17B10PYGLALDH1A1LMNA | |
| SCHEMBL30852390 | 0.81 | GAA (0.39) | KDM4ECYP1A2CYP2C19KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644316-B1 | 2-AMINOBENZOYL DERIVATIVES | NEURIM PHARMA 1991 (IL) | 2010-03-10 | — | — | EP | disclosed |