Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148792 | 0.85 | KDM4E (0.40) | ALDH1A1MAPTPKMLMNAHTT | |
| SCHEMBL3156036 | 0.84 | ACE (0.41) | ALDH1A1MAPTPKMLMNAHTT | |
| SCHEMBL27372856 | 0.82 | PYGL (0.39) | ALDH1A1HSD17B10PYGL | |
| SCHEMBL31520056 | 0.81 | KDM4E (0.51) | PKMRXFP1KDM4E | |
| SCHEMBL148492 | 0.81 | KDM4E (0.51) | PKMRXFP1KDM4E | |
| SCHEMBL31520048 | 0.81 | KDM4E (0.51) | PKMRXFP1KDM4E | |
| SCHEMBL29934103 | 0.81 | KDM4E (0.51) | PKMRXFP1KDM4E | |
| SCHEMBL146329 | 0.81 | KDM4E (0.42) | ALDH1A1MAPTTSHRKDM4EKMT2A | |
| SCHEMBL145723 | 0.81 | KDM4E (0.51) | PKMRXFP1KDM4E | |
| SCHEMBL16801822 | 0.81 | KDM4E (0.51) | PKMRXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3730484-B1 | INDOLEAMINE-2,3-DIOXYGENASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | HINOVA PHARMACEUTICALS INC (CN) | 2024-02-28 | — | — | EP | disclosed |
| US-11447477-B2 | Indoleamine-2,3-dioxygenase inhibitor, the preparative method and the use thereof | HINOVA PHARMACEUTICALS INC. (CN) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447477-B2 | Indoleamine-2,3-dioxygenase inhibitor, the preparative method and the use thereof | IDO1, IDO2, TPH1 | ALDH1A1 504/4885MAPT 2272/4885PKM 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.