Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 2/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489377 | 0.84 | NAMPT (0.44) | NAMPTSLC18A3KCNH2HRH3QDPR | |
| SCHEMBL2452371 | 0.83 | KDM1A (0.48) | NAMPTSLC18A3TLR9TLR8TLR7 | |
| SCHEMBL31489002 | 0.81 | NAMPT (0.61) | NAMPTSLC18A3TLR9TLR8TLR7 | |
| SCHEMBL3080099 | 0.81 | QDPR (0.62) | SLC18A3KCNH2HRH3QDPRCCR1 | |
| SCHEMBL31488955 | 0.80 | NAMPT (0.54) | NAMPTSLC18A3TLR9TLR8TLR7 | |
| SCHEMBL270733 | 0.79 | NAMPT (0.60) | NAMPTHTTRAB9A | |
| SCHEMBL265000 | 0.79 | SLC18A3 (0.51) | NAMPTSLC18A3KCNH2HRH3QDPR | |
| SCHEMBL3634211 | 0.76 | SLC18A3 (0.49) | NAMPTSLC18A3QDPR | |
| SCHEMBL25585276 | 0.76 | SLC18A3 (0.47) | SLC18A3 | |
| SCHEMBL521101 | 0.76 | KCNH2 (0.52) | NAMPTSLC18A3KCNH2HRH3QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |