Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 6/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.41 |
| ▸ | QDPR | P09417 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3527556 | 0.83 | TLR7 (0.47) | NAMPTCYP3A4CYP2C9SLC18A3TLR9 | |
| SCHEMBL31488868 | 0.81 | NAMPT (0.58) | NAMPTCYP3A4CYP2C9SLC18A3TLR9 | |
| SCHEMBL21526404 | 0.81 | SLC18A3 (0.48) | NAMPTCYP3A4CYP2C9SLC18A3TLR9 | |
| SCHEMBL14320271 | 0.79 | TLR9 (0.46) | NAMPTCYP3A4CYP2C9SLC18A3TLR9 | |
| SCHEMBL31489377 | 0.78 | NAMPT (0.44) | NAMPTCYP3A4CYP2C9SLC18A3QDPR | |
| SCHEMBL3080099 | 0.77 | QDPR (0.62) | SLC18A3QDPRKDM1AMAOB | |
| SCHEMBL16255594 | 0.77 | KDM1A (0.45) | NAMPTCYP3A4CYP2C9SLC18A3QDPR | |
| SCHEMBL14320559 | 0.77 | KDM1A (0.45) | NAMPTCYP3A4CYP2C9SLC18A3TLR9 | |
| SCHEMBL24685992 | 0.76 | NAMPT (0.55) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL270733 | 0.76 | NAMPT (0.60) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |