Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 4/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31488868 | 0.84 | NAMPT (0.58) | NAMPTSLC18A3QDPRCYP3A4CYP2C9 | |
| SCHEMBL2452371 | 0.80 | KDM1A (0.48) | NAMPTSLC18A3QDPRCYP3A4CYP2C9 | |
| SCHEMBL21526404 | 0.78 | SLC18A3 (0.48) | NAMPTSLC18A3QDPRCYP3A4CYP2C9 | |
| SCHEMBL31489002 | 0.78 | NAMPT (0.61) | NAMPTSLC18A3QDPRCYP3A4CYP2C9 | |
| SCHEMBL3080099 | 0.77 | QDPR (0.62) | SLC18A3QDPRCCR1KCNH2HRH3 | |
| SCHEMBL270733 | 0.76 | NAMPT (0.60) | NAMPT | |
| SCHEMBL265000 | 0.76 | SLC18A3 (0.51) | NAMPTSLC18A3QDPRKCNH2HRH3 | |
| SCHEMBL25195359 | 0.75 | DRD2 (0.48) | SLC18A3ESRRG | |
| SCHEMBL31488909 | 0.75 | NAMPT (0.52) | NAMPTCYP3A4CYP2C9CCR1 | |
| SCHEMBL3527556 | 0.74 | TLR7 (0.47) | NAMPTSLC18A3CYP3A4CYP2C9HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |