SCHEMBL31489137

SCHEMBL31489137

Cc1ccc(C)n1-c1nc2cc(I)c(F)cn2n1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489657 0.80
SCHEMBL31489379 0.79 KDM4E (0.37) KDM4E
SCHEMBL31489282 0.77
SCHEMBL31489676 0.74 JAK2 (0.34)
SCHEMBL31489677 0.74 JAK2 (0.34)
SCHEMBL31489531 0.73 KDM4E (0.39) KDM4E
SCHEMBL31489336 0.71 PIK3CG (0.38) KDM4E
SCHEMBL31489209 0.69 MAPT (0.32) KDM4E
SCHEMBL31489534 0.69 KDM4E (0.31) KDM4E
SCHEMBL18916742 0.69 AHR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed